Abstract: The practice of the New-democratic Revolution since 1937 fully demonstrates Mao Zedong's practical philosophy. After his systematic conclusion and improvement of philosophical thought in 1937, Mao Zedong not only formed his philosophy of practice, but also had a further understanding and application of Marxism. That was the precondition and foundation for him to form complete theoretical system of the New-democratic Revolution. In Mao Zedong's philosophy of practice, the principle of independence is the important embodiment of national standpoint; seeking truth from facts is the centralized reveal of its objectivity dimension; the mass line is the scientific expression of its subjectivity dimension. Recovering and reproducing Mao’s thinking method and endeavor when facing and solving practical problems are significant to promote the in-depth study, to explore the contemporary value of Mao and to reflect social practice problems from Mao’s perspective.

Key words: Mao Zedong, practice, philosophy, the principle of independence, seeking truth from facts, the mass line